Hardcover, genuine blue top-grain cowhide binding with raised spine lettered in gold and gilt stamped cover design by Daniel B. Bianchi and Selma Ordewer in 22kt gold. 443 pages. Additional refinements include bound in silk ribbon marker, specially commissioned marbled end-papers designed by Richard J. Wolfe and all edges gilt. Edited, with a memoir of the author, by Benjamin W. Richardson. Special limited edition , first edition thus prepared from the first English edition of 1858.. Publisher’s unused original subscriber’s personalized book-plate laid-in loose, indicating that this is copy 921, printed for members of The Classics of Medicine Library. Also included in a two page letter from the editor (folded), giving a brief synopsis of Snow’s life and work as it relates to the present title. Snow was a seminal figure in the fields of epidemiology and anesthesia. His work with chloroform and ether in the present title revolutionized modern surgical practices. No previous ownership marks. A pristine, unread and like new copy. As new.