Hardcover, genuine scarlet pigskin binding with raised spine lettered in gold and cover design and stamping by Daniel B. Bianchi and Selma Ordewer in 22kt gold. 333 pages. Additional refinements include bound in silk ribbon marker, specially commissioned marbled end-papers designed by Richard J. Wolfe and all edges gilt. Includes an index and bibliography, the latter a list of publications from the physiological laboratory in Harvard University, on which the present account is based Special limited edition , first edition thus prepared from the second revised edition of 1939, courtesy of The Francis A. Countway Library of Medicine. Publisher’s unused original subscriber’s personalized book-plate laid-in loose, indicating that this is copy 921, printed for members of The Classics of Medicine Library. The author writes in a clear and accessible manner making his conclusions readily available to both the general public and students of the biological sciences. Focused primarily on physiology, Cannon explores the “relation of the autonomic system to the balance (or, as he terms it, home-ostasis) of physiological processes.” A pristine, unread and like new copy. As new.