Hardcover, genuine maroon top-grain cowhide binding with raised spine lettered in gold and gilt stamped cover design by Daniel B. Bianchi and Selma Ordewer in 22kt gold. 289 pages. 16mo. Additional refinements include bound in silk ribbon marker, specially commissioned marbled end-papers designed by Richard J. Wolfe and all edges gilt. Special limited edition , first edition thus prepared from the first edition of 1683/4.. Publisher’s unused original subscriber’s personalized book-plate laid-in loose, indicating that this is copy 921, printed for members of The Classics of Medicine Library. Bolye, a contemporary and friend of Isaac Newton, was a Anglo-Irish natural philosopher, chemist, physicist, alchemist and inventor. His interests and work the span spectrum from theology to alchemy, albeit his most important contribution to science lay in his application of the scientific method. A pristine, unread and like new copy. As new.